Concerns in Japan over allergic reactions to Pfizer jab, virus variants' spread

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 Japan's health ministry reported Wednesday an extra eight incidents of individuals experiencing severe allergies after receiving a COVID-19 jab, with the minister responsible for vaccination efforts saying such occurrences were high in Japan.


The ministry also said separately that concerns were mounting over the increasing number of individuals testing positive for variants of the novel coronavirus, thought to be particularly contagious.

The Minister responsible for vaccination efforts, Taro Kono, said Wednesday that incidents of anaphylaxis after receiving the coronavirus vaccines developed by U.S. pharmaceutical giant Pfizer and its German partner BioNTech SE were higher in Japan than within us and Europe.

The total cases of anaphylaxis among health care workers being inoculated here have now risen to 25 from 17 reported earlier, the health ministry said. Anaphylaxis may be a potentially lethal and acute allergy to an antigen to which the body has become hypersensitive. "It's true, this seems to be quite within us and Europe," Kono told a Parliamentary Committee after detailing the cases of anaphylaxis reported among around 148,000 health care workers who had been inoculated as of Wednesday.

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By comparison, five cases of anaphylaxis in every 1 million doses given within us are reported and 20 cases per 1 million in Britain. Japan's public broadcaster NHK earlier within the day said the ratio of these going into anaphylaxis after receiving the Pfizer jab in Japan was about 1 in 6,300 people, although the ratio has since increased due to the extra eight cases since reported Wednesday.

According to the health ministry, medical facilities reported that female medical workers aged in their 20s to 50s were those to predominantly experience anaphylaxis after receiving the Pfizer jab, although the primary male case has now also been reported. The symptoms of anaphylaxis include, but aren't limited to, coughing, wheezing, tightness within the chest, general pain, trouble breathing, rapid heartbeat, swollen or itchy throat, tightness within the throat, vomiting, diarrhea, and a weak pulse, health experts here said.

They added that when someone goes into potentially life-threatening anaphylaxis, which among the symptoms will almost certainly include their vital sign suddenly dropping, a narrowing of their airways, and therefore the blocking of normal breathing, they have immediate emergency medical attention. If the reaction isn't treated immediately, it may result in serious complications and may be fatal, they said.

Also, consistent with the experts, one out of each five people may have a second anaphylactic reaction within 12 hours of the primary, referred to as biphasic anaphylaxis. The health ministry said those that experienced anaphylaxis after the Pfizer jab was administered, despite displaying severe reactions, have all since recovered. An investigation led by a panel of experts at the health ministry has been charged with investigating the link between the Pfizer vaccine and therefore the anaphylaxis.

Japan's health minister Norihisa Tamura said a ministry panel will check out the difficulty on Friday and check out to work out whether the symptoms in Japan were as serious as those overseas. Meanwhile, Japan's health ministry on Wednesday said separately that the number of individuals testing positive for variants of the novel coronavirus first detected in Britain, Brazil, and South Africa had reached 345.

The Japanese government has expressed its concern over the spread of the COVID-19 virus variants, known to be more transmissible than the first virus, amid uncertainty whether the vaccines it's procured are going to be effective against the variants. the top of the government's COVID-19 subcommittee, Shigeru Omi, at a parliamentary committee session on Wednesday warned that variants would "become the dominant strain in Japan sooner or later."

Health officials have said that the bulk of individuals infected with the variants in Japan have tested positive for the variant first found in Britain. The variants first found in Brazil and South Africa, however, are thought to be more highly contagious, virologists with knowledge of the matter have attested. because the vaccine rollout campaign continues to expand nationwide in Japan, the govt is ramping up efforts to conduct more polymerase chain reaction (PCR) tests during a bid to detect virus variants.

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