Pfizer working on freeze-dried version of COVID-19 vaccine that doesn’t need ultracold storage

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 Pfizer Inc. PFE, -1.39% and partner BioNTech SE BNTX, +8.89% decide to begin soon testing a freeze-dried version of its COVID-19 vaccine, which is proven to figure safely could ease storage and handling of the shots in rural U.S. areas and low-income countries.


In April, Pfizer is about to start out a clinical test evaluating a so-called lyophilized formulation in adults 18 to 55 years old within the U.S., consistent with a government database, clinicaltrials.gov, and confirmed by the corporate.

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The 1,100-subject study would last about two months, with researchers seeking to work out whether the lyophilized version is as safe and effective because the version authorized by regulators beginning late last year. Researchers would administer to subjects either the lyophilized version of the present formulation.

If successful, the new formulation might be ready to be used by early next year, Pfizer said on an earnings call last month.

Lyophilized vaccines offer advantages to frozen or liquid vaccines because they only need standard refrigeration. which might help with storage and handling and expand access in rural areas and low-income countries that lack specialized equipment. samples of vaccines that will be lyophilized include shots for preventing shingles or rotavirus.

An expanded version of this report appears on WSJ.com.

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